Search on: TACRINE 
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Descriptor English:   Tacrine 
Descriptor Spanish:   Tacrina 
Descriptor Portuguese:   Tacrina 
Synonyms English:   Tetrahydroaminoacridine  
Tree Number:   D03.494.046.250.900
Definition English:   A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. 
Pharmacological Action:   Cholinesterase Inhibitors
Nootropic Agents
Parasympathomimetics
 
History Note English:   91(75); was see under AMINOACRIDINES 1984-90; was see under ACRIDINES 1975-83 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   13996 
Unique Identifier:   D013619 

Occurrence in VHL:
 

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