Search on: TACROLIMUS BINDING PROTEIN 1A 
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Descriptor English:   Tacrolimus Binding Protein 1A 
Descriptor Spanish:   Proteína 1A de Unión a Tacrolimus 
Descriptor Portuguese:   Proteína 1A de Ligação a Tacrolimo 
Synonyms English:   FK506-Binding Protein 1A
FKBP12  
Tree Number:   D08.811.399.325.500.400.700.500
D12.776.543.750.705.400.700.500
D12.776.827.275.700.500
Definition English:   A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS. 
History Note English:   2001; use TACROLIMUS BINDING PROTEINS (NM) 1991-2000 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   35327 
Unique Identifier:   D022061 

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