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TESTOSTERONE-ESTRADIOL BINDING GLOBULIN
Descriptors Found:
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DeCS
Descriptor
English
:
Sex Hormone-Binding Globulin
Descriptor
Spanish
:
Globulina de Unión a Hormona Sexual
Descriptor
Portuguese
:
Globulina de Ligação a Hormônio Sexual
Synonyms
English
:
Testosterone-Estradiol Binding Globulin
Sex Steroid-Binding Protein
Tree Number:
D12.776.124.790.223.800
D12.776.157.762
D12.776.377.715.182.800
Definition
English
:
A glycoprotein migrating as a beta-globulin. Its
molecular weight
, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds
testosterone
,
dihydrotestosterone
, and
estradiol
in the
plasma
.
Sex
hormone-binding protein has the same
amino acid sequence
as
ANDROGEN-BINDING PROTEIN
. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
Indexing Annotation
English
:
does not refer to all
sex
hormones
: refers to a specific protein in the
blood
binding only
testosterone
or
estradiol
; for other
sex
hormone-binding
globulins
consider
ANDROGEN-BINDING PROTEIN
&
PROGESTERONE-BINDING GLOBULIN
; DF: SHBG
See Related
English
:
Androgen-Binding Protein
History Note
English
:
77; SEX STEROID-BINDING PROTEIN was SEX-STEROID-BINDING PROTEIN (NM) 1981-91; ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN were see SEX HORMONE-BINDING GLOBULIN 1977-92
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
22292
Unique Identifier:
D012738
Occurrence in VHL
:
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