Search on: THAPSIGARGIN 
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Descriptor English:   Thapsigargin 
Descriptor Spanish:   Tapsigargina 
Descriptor Portuguese:   Tapsigargina 
Tree Number:   D02.455.426.392.368.284.500.888
D02.455.849.765.793.888
Definition English:   A sesquiterpene lactone found in roots of THAPSIA. It inhibits CA(2+)-TRANSPORTING ATPASE mediated uptake of CALCIUM into SARCOPLASMIC RETICULUM. 
Pharmacological Action:   Enzyme Inhibitors
 
History Note English:   97; was THAPSIGARGIN (NM) 1979-96 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   32986 
Unique Identifier:   D019284 

Occurrence in VHL: 		 

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