Search on: THIAMAZOLE 
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Descriptor English:   Methimazole 
Descriptor Spanish:   Metimazol 
Descriptor Portuguese:   Metimazol 
Synonyms English:   Methymazol
Thiamazole  
Tree Number:   D02.886.489.600
D03.383.129.308.535
Definition English:   A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme. 
Pharmacological Action:   Antithyroid Agents
 
History Note English:   73(68); was see under THYROID ANTAGONISTS 1963-72 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   8890 
Unique Identifier:   D008713 

Occurrence in VHL:
 

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