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THYMIDYLATE SYNTHASE
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DeCS
Descriptor
English
:
Thymidylate Synthase
Descriptor
Spanish
:
Timidilato Sintasa
Descriptor
Portuguese
:
Timidilato Sintase
Tree Number:
D08.811.913.555.500.862
Definition
English
:
An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of
thymidine
triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.
History Note
English
:
98; see METHYLTRANSFERASES 1975-85
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
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history
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isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
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therapeutic use
ultrastructure
urine
Record Number:
14327
Unique Identifier:
D013940
Occurrence in VHL
:
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