Search on:
THYMOTAXIN
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
beta 2-Microglobulin
Descriptor
Spanish
:
Microglobulina-2 beta
Descriptor
Portuguese
:
Microglobulina-2 beta
Synonyms
English
:
Thymotaxin
Tree Number:
D12.776.124.790.223.100
D12.776.377.715.182.100
Definition
English
:
An 11-kDa protein associated with the outer membrane of many
cells
including
lymphocytes
. It is the small subunit of the MHC class I molecule.
Association
with
beta 2-microglobulin
is generally required for the transport of class I heavy chains from the
endoplasmic reticulum
to the cell surface.
Beta 2-microglobulin
is present in small amounts in
serum
, csf, and
urine
of normal people, and to a much greater degree in the
urine
and
plasma
of
patients
with tubular proteinemia, renal failure, or
kidney
transplants.
Indexing Annotation
English
:
/biosyn /physiol
/blood
permitted
History Note
English
:
91(75); was BETA 2 MICROGLOBULIN 1984-90; was see under BETA GLOBULINS 1975-83
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
29233
Unique Identifier:
D001613
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS