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THYROID HORMONE RECEPTORS BETA
Descriptors Found:
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DeCS
Descriptor
English
:
Thyroid Hormone Receptors beta
Descriptor
Spanish
:
Receptores beta de Hormona Tiroidea
Descriptor
Portuguese
:
Receptores beta dos Hormônios Tireóideos
Synonyms
English
:
Receptors beta, Thyroid Hormone
Tree Number:
D12.776.624.664.700.830.750
D12.776.826.850.750
D12.776.930.691.750
Definition
English
:
High affinity receptors for
THYROID HORMONES
, especially
TRIIODOTHYRONINE
. These receptors are usually found in the nucleus where they regulate
DNA
transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by
alternative splicing
. Mutations in the THRB gene cause
THYROID HORMONE RESISTANCE SYNDROME.
History Note
English
:
2003; use RECEPTORS, THYROID HORMONE 1994-2002
Allowable Qualifiers
English
:
administration & dosage
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
chemistry
classification
drug effects
deficiency
genetics
history
immunology
isolation & purification
metabolism
physiology
radiation effects
therapeutic use
ultrastructure
Record Number:
37517
Unique Identifier:
D037042
Occurrence in VHL
:
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