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Descriptor English:   DNA-Directed RNA Polymerases 
Descriptor Spanish:   ARN Polimerasas Dirigidas por ADN 
Descriptor Portuguese:   RNA Polimerases Dirigidas por DNA 
Synonyms English:   DNA-Dependent RNA Polymerases
Transcriptases
RNA Polymerases  
Tree Number:   D08.811.913.696.445.735.270
Definition English:   Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992). 
Indexing Annotation English:   GEN or unspecified; prefer specifics RNA POLYMERASE I, etc.
History Note English:   2003(1973) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   21060 
Unique Identifier:   D012321 

Occurrence in VHL:
 

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