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DeCS
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Descriptor English:
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Transforming Growth Factor beta2
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Descriptor Spanish:
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Factor Transformador de Crecimiento beta2
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Descriptor Portuguese:
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Fator Transformador de Crescimento beta2
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Synonyms English:
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TGF-beta2
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Tree Number:
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D12.644.276.374.687.200
D12.644.276.960.720.200
D12.776.467.374.687.200
D12.776.467.960.720.200
D23.529.374.687.200
D23.529.960.720.200
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Definition English:
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A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. |
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History Note English:
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2007(2000)
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Allowable Qualifiers English:
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Record Number:
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52286
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Unique Identifier:
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D053781
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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