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TRANSFORMING GROWTH FACTOR BETA3
Descriptors Found:
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DeCS
Descriptor
English
:
Transforming Growth Factor beta3
Descriptor
Spanish
:
Factor Transformador de Crecimiento beta3
Descriptor
Portuguese
:
Fator Transformador de Crescimento beta3
Synonyms
English
:
TGF-beta3
Tree Number:
D12.644.276.374.687.300
D12.644.276.960.720.300
D12.776.467.374.687.300
D12.776.467.960.720.300
D23.529.960.720.300
Definition
English
:
A TGF-beta subtype that plays
role
in regulating epithelial-mesenchymal interaction during
embryonic development
. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The
association
of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
History Note
English
:
2007(2000)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
52287
Unique Identifier:
D053782
Occurrence in VHL
:
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