Search on: TRANSFORMING GROWTH FACTORS 
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Descriptor English:   Transforming Growth Factors 
Descriptor Spanish:   Factores Transformadores de Crecimiento 
Descriptor Portuguese:   Fatores Transformadores de Crescimento 
Tree Number:   D12.644.276.960
D12.776.467.960
D23.529.960
Definition English:   Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA. 
Indexing Annotation English:   general or unspecified; prefer specifics
History Note English:   89 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use urine
Record Number:   23851 
Unique Identifier:   D015291 

Occurrence in VHL:
 

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