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DeCS
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Descriptor English:
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Antidepressive Agents, Tricyclic
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Descriptor Spanish:
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Agentes Antidepresivos Triciclicos
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Descriptor Portuguese:
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Antidepressivos Tricíclicos
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Synonyms English:
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Antidepressants, Tricyclic
Tricyclic Antidepressive Agents
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Tree Number:
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D27.505.954.427.700.122.055
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Definition English:
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Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. |
Indexing Annotation English:
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GEN or unspecified; prefer specifics
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History Note English:
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75
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Allowable Qualifiers English:
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Record Number:
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936
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Unique Identifier:
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D000929
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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