Search on: TRYPTOPHAN INDOLE-LYASE 
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Descriptor English:   Tryptophanase 
Descriptor Spanish:   Triptofanasa 
Descriptor Portuguese:   Triptofanase 
Synonyms English:   Tryptophan Indole-Lyase  
Tree Number:   D08.811.520.224.800
Definition English:   An enzyme that catalyzes the conversion of L-tryptophan and water to indole, pyruvate, and ammonia. It is a pyridoxal-phosphate protein, requiring K+. It also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine, and other 3-substituted amino acids. (From Enzyme Nomenclature, 1992) EC 4.1.99.1. 
History Note English:   91(72); was see under LYASES 1972-90 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   14770 
Unique Identifier:   D014368 

Occurrence in VHL:
 

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