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TUFTSIN
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DeCS
Descriptor
English
:
Tuftsin
Descriptor
Spanish
:
Tuftsina
Descriptor
Portuguese
:
Tuftsina
Tree Number:
D12.644.456.840
D12.776.124.486.485.397.500
D12.776.124.486.485.680.650.750
D12.776.124.790.651.397.500
D12.776.124.790.651.680.650.750
D12.776.377.715.548.397.500
D12.776.377.715.548.680.650.750
Definition
English
:
N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the
spleen
by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of
blood
polymorphonuclear
leukocytes
and
neutrophils
in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.
Pharmacological Action:
Immunologic Factors
History Note
English
:
84(75); was see under IMMUNOGLOBULINS, FD 1975-83; LEUKOKININ (with LEUCOKININ a see ref to it) was see under GAMMA GLOBULINS 1975-83; LEUKOKININ & LEUCOKININ were see TUFTSIN 1984-93
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
14807
Unique Identifier:
D014405
Occurrence in VHL
:
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