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TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10
Descriptors Found:
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DeCS
Descriptor
English
:
TNF-Related Apoptosis-Inducing Ligand
Descriptor
Spanish
:
Ligando Inductor de Apoptosis Relacionado con TNF
Descriptor
Portuguese
:
Ligante Indutor de Apoptose Relacionado a TNF
Synonyms
English
:
Tumor Necrosis Factor Ligand Superfamily Member 10
Tree Number:
D12.644.276.374.750.625
D12.644.276.972.625
D12.776.467.374.750.625
D12.776.467.972.625
D23.529.374.750.625
D23.529.972.625
Definition
English
:
A transmembrane-protein belonging to the TNF
family
of intercellular signaling
proteins
. It is a widely expressed ligand that activates
APOPTOSIS
by binding to
TNF-RELATED APOPTOSIS-INDUCING LIGAND
RECEPTORS. The membrane-bound form of the protein can be cleaved by specific
CYSTEINE ENDOPEPTIDASES
to form a soluble ligand form.
History Note
English
:
2007(2005)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
52298
Unique Identifier:
D053221
Occurrence in VHL
:
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