Search on: TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14 
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Descriptor English:   Receptors, Tumor Necrosis Factor, Member 14 
Descriptor Spanish:   Miembro 14 de Receptores de Factores de Necrosis Tumoral 
Descriptor Portuguese:   Membro 14 de Receptores de Fatores de Necrose Tumoral 
Synonyms English:   Herpesvirus Entry Mediator
Tumor Necrosis Factor Receptor Superfamily, Member 14  
Tree Number:   D12.776.543.750.705.852.760.500
D12.776.543.750.925.850
Definition English:   A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS. 
History Note English:   2007(1997) 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   52393 
Unique Identifier:   D053240 

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