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TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 4
Descriptors Found:
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DeCS
Descriptor
English
:
Receptors, OX40
Descriptor
Spanish
:
Receptores OX40
Descriptor
Portuguese
:
Receptores OX40
Synonyms
English
:
Antigens, CD134
CD134 Antigens
Receptors, Tumor Necrosis Factor, Member 4
Tumor Necrosis Factor Receptor Superfamily, Member 4
Tree Number:
D12.776.543.750.705.852.760.350
D23.050.301.264.035.855
D23.101.100.110.855
Definition
English
:
A tumor
necrosis
family
receptor with specificity for
OX40 LIGAND
. It is found on the surface of activated
T-LYMPHOCYTES
where it plays a
role
in enhancing cytokine production and proliferation of
CD4-POSITIVE T-LYMPHOCYTES
. Signaling by the activated receptor occurs through its
association
with TNF RECEPTOR-ASSOCIATED FACTORS.
History Note
English
:
2007(1993)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
52392
Unique Identifier:
D053262
Occurrence in VHL
:
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