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ALPHA 1-ANTITRYPSIN
Descriptors Found:
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DeCS
Descriptor
English
:
alpha 1-Antitrypsin
Descriptor
Spanish
:
alfa 1-Antitripsina
Descriptor
Portuguese
:
alfa 1-Antitripsina
Synonyms
English
:
Trypsin Inhibitor, alpha 1-Antitrypsin
alpha 1-Protease Inhibitor
alpha 1-Proteinase Inhibitor
Tree Number:
D12.644.822.374
D12.776.124.050.070
D12.776.124.790.106.085
D12.776.377.715.085.085
D12.776.645.374
D12.776.872.035
Definition
English
:
Plasma glycoprotein member of the serpin superfamily which inhibits
TRYPSIN
; NEUTROPHIL ELASTASE; and other PROTEOLYTIC
ENZYMES
. Commonly referred to as alpha 1-proteinase inhibitor (A1PI), it exists in over 30 different biochemical variant
forms
known collectively as the Pi (protease inhibitor) system. Hereditary A1PI deficiency is associated with
PULMONARY EMPHYSEMA.
Pharmacological Action:
Serine Proteinase Inhibitors
Trypsin Inhibitors
Entry Combination - descr/qualif
English
:
alpha 1-Antitrypsin
/
deficiency
use
alpha 1-Antitrypsin Deficiency
See Related
English
:
alpha 1-Antitrypsin Deficiency
History Note
English
:
74
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
27940
Unique Identifier:
D000515
Occurrence in VHL
:
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