DeCS Server - List Exact Term

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DeCS

Descriptor English:

beta 2-Microglobulin

Descriptor Spanish:

Microglobulina-2 beta

Descriptor Portuguese:

Microglobulina-2 beta

Synonyms English:

Thymotaxin

Tree Number:

Definition English:

An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.

Indexing Annotation English:

/biosyn /physiol /blood permitted

History Note English:

91(75); was BETA 2 MICROGLOBULIN 1984-90; was see under BETA GLOBULINS 1975-83

Allowable Qualifiers English:

Record Number:

29233

Unique Identifier:

D001613

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