Search on: BETA-AMYLOID PROTEIN 
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Descriptor English:   Amyloid beta-Protein 
Descriptor Spanish:   Proteína beta Amiloide 
Descriptor Portuguese:   Proteína beta Amilóide 
Synonyms English:   Alzheimer beta-Protein
Amyloid Fibril Protein (Alzheimer's)
Amyloid Protein A4
beta-Amyloid Protein  
Tree Number:   D12.776.049.025
Definition English:   A 4-kDa protein, 39-43 amino acids long, expressed by a gene located on chromosome 21. It is the major protein subunit of the vascular and plaque amyloid filaments in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The protein is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue. 
Indexing Annotation English:   /biosyn /drug eff /physiol /ultrastruct permitted
See Related English:   Cerebral Amyloid Angiopathy
 
History Note English:   91 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   28856 
Unique Identifier:   D016229 

Occurrence in VHL:
 

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