Search on: BETA-ENDOTHELIAL GROWTH FACTOR 
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Descriptor English:   Endothelial Growth Factors 
Descriptor Spanish:   Factores de Crecimiento Endotelial 
Descriptor Portuguese:   Fatores de Crescimento Endotelial 
Synonyms English:   alpha-Endothelial Growth Factor
beta-Endothelial Growth Factor
Endothelial Cell-Derived Growth Factors  
Tree Number:   D12.644.276.390
D12.776.467.390
D23.529.390
Definition English:   These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences. 
Indexing Annotation English:   do not confuse with EGF; (EPIDERMAL GROWTH FACTOR)
Pharmacological Action:   Growth Substances
 
See Related English:   Vascular Endothelial Growth Factor A
 
History Note English:   91 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
urine  
Record Number:   28920 
Unique Identifier:   D016228 

Occurrence in VHL:
 

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