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DeCS
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Descriptor English:
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Antibodies, Antineutrophil Cytoplasmic
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Descriptor Spanish:
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Anticuerpos Citoplasmáticos Antineutrófilo
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Descriptor Portuguese:
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Anticorpos Anticitoplasma de Neutrófilos
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Synonyms English:
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c-ANCA
p-ANCA
Antineutrophil Cytoplasmic Antibodies
ANCA
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Tree Number:
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D12.776.124.486.485.114.323.190
D12.776.124.790.651.114.323.190
D12.776.377.715.548.114.323.190
D23.101.050
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Definition English:
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Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for WEGENER GRANULOMATOSIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA. |
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Indexing Annotation English:
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do not coordinate with ANTIBODY FORMATION for /biosyn;
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Pharmacological Action:
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Immunologic Factors
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History Note English:
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97; was C-ANCA (NM) 1991-96
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Allowable Qualifiers English:
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Record Number:
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33077
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Unique Identifier:
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D019268
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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