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C-BCL-1 PROTEINS
Descriptors Found:
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DeCS
Descriptor
English
:
Cyclin D1
Descriptor
Spanish
:
Ciclina D1
Descriptor
Portuguese
:
Ciclina D1
Synonyms
English
:
bcl-1 Proto-Oncogene Proteins
c-bcl-1 Proteins
CCND1 Protein
Proto-Oncogene Proteins c-bcl-1
PRAD1 Protein
Tree Number:
D12.644.360.262.161
D12.776.167.218.161
D12.776.476.262.161
D12.776.624.664.700.100
Definition
English
:
Protein encoded by the bcl-1 gene which plays a critical
role
in regulating the
cell cycle
. Overexpression of
cyclin D1
is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various
neoplasms.
Entry Combination - descr/qualif
English
:
Cyclin D1
/
analogs & derivatives
use
Cyclins
See Related
English
:
Lymphoma, Mantle-Cell
History Note
English
:
98; use CYCLIN D1 (NM) 1990-97
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
33482
Unique Identifier:
D019938
Occurrence in VHL
:
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