Search on: C-BCL-2 PROTEINS 
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Descriptor English:   Proto-Oncogene Proteins c-bcl-2 
Descriptor Spanish:   Proteínas Proto-Oncogénicas c-bcl-2 
Descriptor Portuguese:   Proteínas Proto-Oncogênicas c-bcl-2 
Synonyms English:   bcl-2 Proto-Oncogene Proteins
c-bcl-2 Proteins  
Tree Number:   D12.644.360.075.718
D12.776.476.075.718
D12.776.624.664.700.169
Definition English:   Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma. 
History Note English:   97; was PROTO-ONCOGENE PROTEIN BCL-2 (NM) 1989-96 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   33061 
Unique Identifier:   D019253 

Occurrence in VHL:
 

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