Search on: C-MDM2 PROTO-ONCOGENE PROTEIN 
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Descriptor English:   Proto-Oncogene Proteins c-mdm2 
Descriptor Spanish:   Proteínas Proto-Oncogénicas c-mdm2 
Descriptor Portuguese:   Proteínas Proto-Oncogênicas c-mdm2 
Synonyms English:   c-mdm2 Proto-Oncogene Protein
Mdm2 Protein  
Tree Number:   D08.811.464.938.750.562
D12.776.624.664.700.185
D12.776.660.764
Definition English:   An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF. 
History Note English:   2006(1991) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   50587 
Unique Identifier:   D051736 

Occurrence in VHL: 		 

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