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C-RET PROTEIN
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DeCS
Descriptor
English
:
Proto-Oncogene Proteins c-ret
Descriptor
Spanish
:
Proteínas Proto-Oncogénicas c-ret
Descriptor
Portuguese
:
Proteínas Proto-Oncogênicas c-ret
Synonyms
English
:
c-ret Protein
ret Proto-Oncogene Proteins
Tree Number:
D08.811.913.696.620.682.725.400.087
D12.776.543.750.060.217
D12.776.624.664.700.194
Definition
English
:
Receptor
protein-tyrosine kinases
involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC FACTOR
ligands
. They contain an extracellular cadherin domain and form a receptor complexes with GDNF RECEPTORS. Mutations in ret protein are responsible for
HIRSCHSPRUNG DISEASE
and
MULTIPLE ENDOCRINE NEOPLASIA
TYPE 2.
History Note
English
:
2006(1999)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
50737
Unique Identifier:
D051096
Occurrence in VHL
:
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