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DeCS
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Descriptor English:
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Receptor, trkA
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Descriptor Spanish:
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Receptor trqA
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Descriptor Portuguese:
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Receptor trkA
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Synonyms English:
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gp140(c-TRK)
trk Proto-Oncogene Protein
trkA Receptor
NTRK1 Receptor
Proto-Oncogene Protein trk
Receptor, Neurotrophic Tyrosine Kinase Type 1
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Tree Number:
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D08.811.913.696.620.682.725.400.660
D12.776.543.750.060.496
D12.776.543.750.750.400.550.550
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Definition English:
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A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with congenital insensitivity to pain with anhidrosis, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis. |
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Indexing Annotation English:
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DF: RECEPT TRKA
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History Note English:
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2000; use RECEPTOR, TYPE 1 NEUROTROPHIC TYROSINE KINASE(NM) 1990-1999
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Allowable Qualifiers English:
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Record Number:
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34455
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Unique Identifier:
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D020917
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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