Search on: BIOTRANSFORMATION 
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Descriptor English:   Biotransformation 
Descriptor Spanish:   Biotransformación 
Descriptor Portuguese:   Biotransformação 
Synonyms English:   Metabolic Activation  
Tree Number:   G06.535.780.202
G12.091.690.140
Definition English:   The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II. 
Indexing Annotation English:   restrict to chemical changes of exogenous substances; IM general only; coordinate NIM with specific drug /pharmacokin (IM); or /metab (for microorganisms); do not confuse with BIODEGRADATION, ENVIRONMENTAL: elimination of pollutants, pesticides & other wastes by living organisms
History Note English:   70(66) 
Allowable Qualifiers English:  
drug effects ethics
genetics immunology
physiology radiation effects
Record Number:   23169 
Unique Identifier:   D001711 

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