Search on: RENIN 
Descriptors Found: 1
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Descriptor English:   Renin 
Descriptor Spanish:   Renina 
Descriptor Portuguese:   Renina 
Synonyms English:   Angiotensin-Forming Enzyme
Angiotensinogenase  
Tree Number:   D08.811.277.656.300.066.780
D08.811.277.656.837.750
Definition English:   A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19. 
Indexing Annotation English:   do not confuse with RENNIN see CHYMOSIN
History Note English:   1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   29553 
Unique Identifier:   D012083 

Occurrence in VHL: 		 

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