Search on: SYNAPSINS 
Descriptors Found: 1
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Descriptor English:   Synapsins 
Descriptor Spanish:   Sinapsinas 
Descriptor Portuguese:   Sinapsinas 
Synonyms English:   Synapsin I
Synapsin II
Synapsin III  
Tree Number:   D12.776.641.750
D12.776.744.840
Definition English:   A family of synaptic vesicle-associated proteins involved in the short-term regulation of NEUROTRANSMITTER release. Synapsin I, the predominant member of this family, links SYNAPTIC VESICLES to ACTIN FILAMENTS in the presynaptic nerve terminal. These interactions are modulated by the reversible PHOSPHORYLATION of synapsin I through various signal transduction pathways. The protein is also a substrate for cAMP- and CALCIUM-CALMODULIN DEPENDENT PROTEIN KINASES. It is believed that these functional properties are also shared by synapsin II. 
History Note English:   1992; use SYNAPSINS (NM) 1981-1991 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   29796 
Unique Identifier:   D016704 

Occurrence in VHL:
 

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