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ANGIOPOIETIN-1
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DeCS
Descriptor
English
:
Angiopoietin-1
Descriptor
Spanish
:
Angiopoyetina 1
Descriptor
Portuguese
:
Angiopoietina-1
Tree Number:
D12.644.276.100.100.100
D12.776.467.100.100.100
D23.529.100.100.100
Definition
English
:
The first to be discovered member of the angiopoietin
family
. It may play a
role
in increasing the sprouting and branching of
BLOOD VESSELS
.
Angiopoietin-1
specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of
angiopoietin-1
occur due to
ALTERNATIVE SPLICING
of its mRNA.
Indexing Annotation
English
:
see SCR for organism-specific terms
History Note
English
:
2004; use ANGIOPOIETIN-1 (NM) 1997-2003
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
38238
Unique Identifier:
D042683
Occurrence in VHL
:
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