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FURIN
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DeCS
Descriptor
English
:
Furin
Descriptor
Spanish
:
Furina
Descriptor
Portuguese
:
Furina
Synonyms
English
:
Dibasic Processing Enzyme
Tree Number:
D08.811.277.656.300.760.353
D08.811.277.656.837.249
Definition
English
:
A proprotein convertase with specificity for the proproteins of PROALBUMIN; COMPLEMENT 3C; and
VON WILLEBRAND FACTOR
. It has specificity for cleavage near paired
ARGININE
residues that are separated by two
amino acids.
History Note
English
:
2004; use FURIN (NM) 1993-2003
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
38168
Unique Identifier:
D045683
Occurrence in VHL
:
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