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KARYOPHERINS
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DeCS
Descriptor
English
:
Karyopherins
Descriptor
Spanish
:
Carioferinas
Descriptor
Portuguese
:
Carioferinas
Synonyms
English
:
Importins
Tree Number:
D12.776.157.530.750.500
D12.776.543.585.750.500
D12.776.660.502
Definition
English
:
A
family
of
proteins
involved in NUCLEOCYTOPLASMIC TRANSPORT.
Karyopherins
are heteromeric molecules composed two major types of components,
ALPHA KARYOPHERINS
and
BETA KARYOPHERINS
, that function together to transport molecules through the
NUCLEAR PORE
COMPLEX. Several other
proteins
such as RAN GTP BINDING PROTEIN and
CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN
bind to
karyopherins
and participate in the transport process.
See Related
English
:
Active Transport, Cell Nucleus
History Note
English
:
2002; use KARYOPHERINS (NM) 1995-2001
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
36191
Unique Identifier:
D028884
Occurrence in VHL
:
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