Search on:
QUININE
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Quinine
Descriptor
Spanish
:
Quinina
Descriptor
Portuguese
:
Quinina
Tree Number:
D03.132.206.719
D03.438.810.762
D03.605.687.762
Definition
English
:
An alkaloid derived from the bark of the
cinchona
tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the
cinchona
that have been used for that purpose since before 1633.
Quinine
is also a mild antipyretic and analgesic and has been used in
common cold
preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of
babesiosis
.
Quinine
is also useful in some muscular disorders, especially nocturnal
leg
cramps and
myotonia congenita
, because of its direct effects on muscle membrane and
sodium channels
. The mechanisms of its antimalarial effects are not well understood.
Indexing Annotation
English
:
/biosyn permitted if by plant
Pharmacological Action:
Analgesics, Non-Narcotic
Antimalarials
Muscle Relaxants, Central
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
12240
Unique Identifier:
D011803
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS