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UROPORPHYRINOGENS
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DeCS
Descriptor
English
:
Uroporphyrinogens
Descriptor
Spanish
:
Uroporfirinógenos
Descriptor
Portuguese
:
Uroporfirinogênios
Tree Number:
D03.383.129.578.840.500.700.900
D03.549.909.500.700.900
D04.345.783.500.700.900
D23.767.727.700.900
Definition
English
:
Porphyrinogens which are intermediates in
heme
biosynthesis. They have four
acetic acid
and four propionic acid side chains attached to the pyrrole rings. Uroporphyrinogen I and III are formed from polypyrryl
methane
in the presence of uroporphyrinogen III cosynthetase and uroporphyrin I synthetase, respectively. They can yield
uroporphyrins
by autooxidation or
coproporphyrinogens
by
decarboxylation.
Indexing Annotation
English
:
porphyrins
History Note
English
:
91(76); was see under PORPHYRINOGENS 1976-90
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
14979
Unique Identifier:
D014577
Occurrence in VHL
:
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