Search on: BETA-MANNOSIDASE 
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Descriptor English:   beta-Mannosidase 
Descriptor Spanish:   beta-Manosidasa 
Descriptor Portuguese:   beta-Manosidase 
Synonyms English:   beta-D-Mannosidase  
Tree Number:   D08.811.277.450.625.750
Definition English:   An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS. 
Indexing Annotation English:   /defic: consider also BETA-MANNOSIDOSIS
See Related English:   beta-Mannosidosis
 
History Note English:   2004; use BETA-MANNOSIDASE (NM) 1980-2003 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   38164 
Unique Identifier:   D044902 

Occurrence in VHL:
 

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