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O,P-DDD
Descriptors Found:
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DeCS
Descriptor
English
:
Mitotane
Descriptor
Spanish
:
Mitotano
Descriptor
Portuguese
:
Mitotano
Synonyms
English
:
o,p-DDD
ortho,para-DDD
Tree Number:
D02.455.526.439.681
Definition
English
:
A derivative of the insecticide
DICHLORODIPHENYLDICHLOROETHANE
that specifically inhibits
cells
of the
adrenal cortex
and their production of
hormones
. It is used to treat adrenocortical tumors and causes CNS damage, but no
bone marrow
depression.
Indexing Annotation
English
:
TN 111 for eff on
insects
Pharmacological Action:
Antineoplastic Agents, Hormonal
History Note
English
:
73
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
9129
Unique Identifier:
D008939
Occurrence in VHL
:
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