Search on: CORTISONE 
Descriptors Found: 1
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Descriptor English:   Cortisone 
Descriptor Spanish:   Cortisona 
Descriptor Portuguese:   Cortisona 
Tree Number:   D04.808.745.745.183
D06.472.040.585.478.195
Definition English:   A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726) 
Indexing Annotation English:   /biosyn/physiol permitted
Pharmacological Action:   Anti-Inflammatory Agents
 
History Note English:   /adv eff-pois-tox was CORTISONE TOXICOLOGY 1963-65; /ther use was CORTISONE, THERAPEUTIC 1965 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use urine
Record Number:   22406 
Unique Identifier:   D003348 

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