Search on: PARAPROTEINS 
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Descriptor English:   Paraproteins 
Descriptor Spanish:   Paraproteínas 
Descriptor Portuguese:   Paraproteínas 
Tree Number:   D12.776.124.486.485.900
D12.776.124.790.651.900
D12.776.377.715.548.900
Definition English:   Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered. 
Pharmacological Action:   Immunologic Factors
 
History Note English:   76; was see under GLOBULINS 1963-65 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   22253 
Unique Identifier:   D010266 

Occurrence in VHL: 		 

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