Search on: PROTHROMBIN 
Descriptors Found: 1
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Descriptor English:   Prothrombin 
Descriptor Spanish:   Protrombina 
Descriptor Portuguese:   Protrombina 
Synonyms English:   Factor II
Coagulation Factor II  
Tree Number:   D08.622.709
D12.776.124.125.800
D23.119.945
Definition English:   A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia. 
Indexing Annotation English:   a blood coag factor; an enzyme precursor
Entry Combination - descr/qualif English:   Prothrombin/deficiency use Hypoprothrombinemias
 
See Related English:   Coagulants
 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
biosynthesis cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   22270 
Unique Identifier:   D011516 

Occurrence in VHL: 		 

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