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DeCS
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Descriptor English:
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Tissue Plasminogen Activator
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Descriptor Spanish:
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Activador de Tejido Plasminógeno
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Descriptor Portuguese:
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Ativador de Plasminogênio Tecidual
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Synonyms English:
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Tissue-Type Plasminogen Activator
Plasminogen Activator, Tissue-Type
Alteplase
T-Plasminogen Activator
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Tree Number:
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D08.811.277.656.300.760.875
D12.776.124.125.662.768
D23.119.970
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Definition English:
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A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to PLASMIN. It has fibrin-binding activity and is immunologically different from URINARY PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases. EC 3.4.21.68. |
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Indexing Annotation English:
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DF: TTPA
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Pharmacological Action:
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Fibrinolytic Agents
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History Note English:
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98(86)
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Allowable Qualifiers English:
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Record Number:
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30438
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Unique Identifier:
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D010959
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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