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PLASMINOGEN
Descriptors Found:
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DeCS
Descriptor
English
:
Plasminogen
Descriptor
Spanish
:
Plasminógeno
Descriptor
Portuguese
:
Plasminogênio
Synonyms
English
:
Profibrinolysin
Tree Number:
D08.622.610
D12.776.124.790.223.580
D12.776.377.715.182.580
Definition
English
:
Precursor of fibrinolysin (plasmin). It is a single-chain beta-globulin of
molecular weight
80-90,000 found mostly in
association
with
fibrinogen
in
plasma
;
plasminogen activators
change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.
Indexing Annotation
English
:
an enzyme precursor & fibrinolytic agent; /antag: do not confuse with
PLASMINOGEN INACTIVATORS
which modulate
PLASMINOGEN ACTIVATORS
, not
PLASMINOGEN
Pharmacological Action:
Fibrinolytic Agents
History Note
English
:
65(63)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
11392
Unique Identifier:
D010958
Occurrence in VHL
:
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