Search on: TOXIN-ANTIBODY CONJUGATES 
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Descriptor English:   Immunotoxins 
Descriptor Spanish:   Inmunotoxinas 
Descriptor Portuguese:   Imunotoxinas 
Synonyms English:   Antibody-Toxin Conjugates
Antibody-Toxin Hybrids
Cytotoxin-Antibody Conjugates
Targeted Toxins
Toxin-Antibody Conjugates
Toxin-Antibody Hybrids
Toxin Carriers
Toxin Conjugates
Toxins, Targeted
Chimeric Toxins
Toxins, Chimeric  
Tree Number:   D12.776.124.486.485.114.580.450
D12.776.124.790.651.114.580.450
D12.776.377.715.548.114.580.450
D27.888.569.271
Definition English:   Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant TOXINS, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect. 
Indexing Annotation English:   coordinate IM with specific toxin (IM) + specific immune substance (NIM)
Pharmacological Action:   Immunologic Factors
 
History Note English:   90; was ANTIBODY-TOXIN CONJUGATES 1987-89 
Allowable Qualifiers English:  
administration & dosage adverse effects
analysis blood
cerebrospinal fluid chemistry
classification contraindications
drug effects diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
toxicity therapeutic use
ultrastructure urine
Record Number:   28229 
Unique Identifier:   D000922 

Occurrence in VHL:
 

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