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AMITRIPTYLINE
Descriptors Found:
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DeCS
Descriptor
English
:
Amitriptyline
Descriptor
Spanish
:
Amitriptilina
Descriptor
Portuguese
:
Amitriptilina
Tree Number:
D02.455.426.559.847.181.384.100
D04.615.181.384.100
Definition
English
:
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of
norepinephrine
and
serotonin
at nerve terminals, thus potentiating the action of these neurotransmitters.
Amitriptyline
also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive
amines.
Pharmacological Action:
Adrenergic Uptake Inhibitors
Analgesics, Non-Narcotic
Antidepressive Agents, Tricyclic
History Note
English
:
64(63)
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
652
Unique Identifier:
D000639
Occurrence in VHL
:
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