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ANCROD
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DeCS
Descriptor
English
:
Ancrod
Descriptor
Spanish
:
Ancrod
Descriptor
Portuguese
:
Ancrod
Synonyms
English
:
Agkistrodon rhodostoma Venom Protease
Agkistrodon Serine Proteinase
Tree Number:
D08.811.277.656.300.760.955.060
D20.888.850.960.200.050
D23.946.833.850.960.200.050
Definition
English
:
An enzyme fraction from the venom of the Malayan pit viper,
Agkistrodon
rhodostoma. It catalyzes the
hydrolysis
of a number of amino acid
esters
and a limited proteolysis of
fibrinogen
. It is used clinically to produce controlled defibrination in
patients
requiring anticoagulant therapy. EC 3.4.21.-.
Pharmacological Action:
Anticoagulants
Fibrinolytic Agents
History Note
English
:
78; was ARVIN see under ENDOPEPTIDASES 1975-77; ARVIN was see ANCROD 1978-95
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
23155
Unique Identifier:
D000721
Occurrence in VHL
:
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DeCS
SciELO
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