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FIBRINOGEN
Descriptors Found:
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DeCS
Descriptor
English
:
Fibrinogen
Descriptor
Spanish
:
Fibrinógeno
Descriptor
Portuguese
:
Fibrinogênio
Synonyms
English
:
Factor I
Coagulation Factor I
Tree Number:
D12.776.124.050.250
D12.776.124.125.500
D12.776.811.300
D23.119.490
Definition
English
:
Plasma glycoprotein clotted by
thrombin
, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds.
Fibrinogen
clotting is a sol-gel change involving complex molecular arrangements: whereas
fibrinogen
is cleaved by
thrombin
to form polypeptides A and B, the proteolytic action of other
enzymes
yields different
fibrinogen
degradation products.
Indexing Annotation
English
:
a
blood
coag factor: do not confuse X ref FACTOR I with
COMPLEMENT FACTOR I
Entry Combination - descr/qualif
English
:
Fibrinogen
/
deficiency
use
Afibrinogenemia
See Related
English
:
Coagulants
Hemostatics
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
22179
Unique Identifier:
D005340
Occurrence in VHL
:
Similar:
DeCS
SciELO
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