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CYCLINS
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DeCS
Descriptor
English
:
Cyclins
Descriptor
Spanish
:
Ciclinas
Descriptor
Portuguese
:
Ciclinas
Tree Number:
D12.644.360.262
D12.776.167.218
D12.776.476.262
Definition
English
:
Regulatory
proteins
that function in the
cell cycle
to activate maturation promoting factor. They complex with p34cdc2 (PROTEIN P34CDC2), the catalytic subunit of
MATURATION-PROMOTING FACTOR
, and modulate its protein kinase activity.
Cyclins
themselves have no enzymatic activity.
Indexing Annotation
English
:
regulatory
proteins
;
growth substances
; do not confuse with the nuclear protein cyclin (PCNA or Proliferating Cell Nuclear Antigen); note specifics
See Related
English
:
Maturation-Promoting Factor
History Note
English
:
93; was CYCLIN 1991-2
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
30942
Unique Identifier:
D016213
Occurrence in VHL
:
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