Search on: IONOPHORES 
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Descriptor English:   Ionophores 
Descriptor Spanish:   Ionóforos 
Descriptor Portuguese:   Ionóforos 
Tree Number:   D27.505.519.562.374
D27.720.395
Definition English:   Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes. 
See Related English:   Cell Membrane Permeability
 
History Note English:   76 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications diagnostic use
economics history
immunology isolation & purification
metabolism pharmacology
pharmacokinetics poisoning
radiation effects supply & distribution
standards toxicity
therapeutic use urine
Record Number:   7644 
Unique Identifier:   D007476 

Occurrence in VHL:
 

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