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LIPOPOLYSACCHARIDES
Descriptors Found:
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DeCS
Descriptor
English
:
Lipopolysaccharides
Descriptor
Spanish
:
Lipopolisacáridos
Descriptor
Portuguese
:
Lipopolissacarídeos
Tree Number:
D09.400.500
D09.698.718.450
D10.494
D23.050.161.616.525
D23.946.123.329.500
Definition
English
:
Lipid-containing
polysaccharides
which are
endotoxins
and important group-specific
antigens
. They are often derived from the
cell wall
of
gram-negative bacteria
and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts:
LIPID A
, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from
Escherichia coli
,
lipopolysaccharides
serve as polyclonal B-cell
mitogens
commonly used in laboratory immunology. (From Dorland, 28th ed)
Indexing Annotation
English
:
largely bacterial so do not coord with
POLYSACCHARIDES
, BACTERIAL for bacterial
lipopolysaccharides
; coord IM with specific bacterium (IM); DF: LPS
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
28155
Unique Identifier:
D008070
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS